Artichoke Chicken and Spinach Lasagna

Artichoke Chicken and Spinach Lasagna

Classic lasagna gets a modern twist in this delectable artichoke, chicken and spinach lasagna. You’ll find some of the usual suspects like ricotta and mozzarella but a creamy Parmesan sauce takes the place of tomato sauce.

It all adds up to layer upon layer of decadence. Tasty, tender pieces of chicken with the bite of tangy artichokes and fresh baby spinach surrounded by oodles of cheese all held together by a rich sauce and layers of fresh pasta noodles.


I can’t tell you how fast this disappeared. I ate leftovers for breakfast the next day and the vegetable hater in my house ate more than his fair share.

To save time use fresh pasta noodles you can find in the refrigerated pasta section of your market or use the no-bake kind so you can skip that step of boiling the noodles. My Mom swears by the Barila brand – she uses them without fail all the time.

Chicken and Spinach Artichoke  Lasagna

Anyone who’s made a lasagna before knows there’s two things to worry about most. One is that it holds together and second that it isn’t dry. There’s a fine line between too much sauce and just the right amount.

I pulled it off.

This has the perfect amount of sauce so as not to be dry but not so much that the layers slide off each other. Not that there’s anything wrong with that. Some of the most delicious lasagna I’ve ever eaten was one hot mess that just collapsed into a saucy pile when served.

This is not that but something other worldly delicious.

Artichoke Chicken Lasagna

Artichoke Chicken and Spinach Lasagna

Rating: 51

Prep Time: 1 hour

Cook Time: 50 minutes

Yield: 12 squares

Artichoke Chicken and Spinach Lasagna

Classic lasagna gets a modern twist in this delectable artichoke, chicken and spinach lasagna.


2 tablespoons olive oil
1/4 cup diced onion
4 cloves garlic, minced
1 pound boneless chicken breasts, cut into cubes
1 teaspoon Italian seasoning
coarse salt and fresh black pepper
2 (14 ounce) cans (or frozen) artichoke hearts, well-drained
2 cups ricotta Cheese
2 cups fresh shredded mozzarella cheese, divided
1 beaten egg
1 tablespoon fresh chopped parsley
3 cups fresh baby spinach leaves, stems removed
1 pound lasagna noodles, preferably fresh
4 tablespoons butter
1/4 cup all-purpose flour
2 cups whole milk
dash of nutmeg
1/2 cup fresh grated Parmesan cheese
coarse salt and fresh black pepper


  1. In a large skillet heat the olive oil over medium-low heat. Add the onion, garlic, chicken, Italian seasoning and season well with salt and pepper.
  2. Cook, stirring often until chicken is cooked through. Cut the artichokes in half and then in half again, dry off any moisture with paper towels. Stir them into the chicken and cook 2 - 3 minutes. Remove from heat and allow to cool.
  3. In a large mixing bowl combine the ricotta, 1 + 1/2 cups of the mozzarella, the egg and parsley.
  4. Make stacks out of the spinach leaves and cut them into thin strips (chiffonade). Mix them into the ricotta mixture - it will be thick.
  5. Make the sauce:
  6. In a large, heavy duty saucepan melt the butter over medium-low heat. Whisk in flour and cook 3 - 4 minutes, whisking often. Slowly whisk in milk, turn heat up and bring to a simmer.
  7. Maintain a simmer for 4 minutes, stirring often. Turn heat down to low and stir in nutmeg, Parmesan cheese and a pinch or two each of salt and pepper, continue stirring until cheese is melted. Remove from heat.
  8. If using dried noodles cook according to package directions.
  9. Assemble the lasagna:
  10. Preheat oven to 375 degrees F. Butter a 9 x 13-inch casserole pan.
  11. Add a very thin layer of sauce over bottom of the pan, then a layer of noodles covering the bottom completely from edge to edge. Spread 1/2 the ricotta mixture evenly from edge to edge then top with 1/3 of the chicken mixture followed by 1/3 of the sauce.
  12. Cover the filling with another layer of noodles followed with the remaining 1/2 of ricotta, 1/3 of the chicken and 1/3 of the sauce.
  13. Cover with another layer of noodles followed by the remaining sauce, the remaining chicken mixture and the 1/2 cup mozzarella cheese.
  14. Bake 45 - 50 minutes until bubbly and hot in the middle. If the top starts to get too brown tent with aluminum foil. Allow to set 5 - 10 minutes before cutting into squares and serving.


Copyright ©2013 Cinnamon Spice and Everything Nice by Reeni Pisano All Rights Reserved. No copying or duplication of any content (including photos) without the express written permission from the owner of this website.




  1. Suzanne says

    Reeni, this lasagna looks so good, I love how creamy it looks and with chicken and spinach sounds delish. I can’t wait to try it out!

  2. Riley says

    Have you tried preparing this and freezing it? Would it be best to cook it first then freeze and reheat? Thanks!

    • Reeni says

      Hi Riley! I don’t do any type of freezer cooking. . . you would probably want to cook it first? Whatever method you usually use for casseroles should work here. Sorry I can’t be of more help!

      • Natasha says

        Hi, you should be able to assemble and freeze without baking, unless you used frozen chokes. If you bake before freezing you’ll want to leave the foil on the whole time so you can brown it up without burning when you heat. I’m gonna add some zucchini to the chicken when I make this… just ’cause I have a ton of it.

  3. Shala says

    Hi! This looks great! Can this be prepared the night before and baked the next day? I wasnt’ sure if that would be okay if using the no-boil lasagna noodles. Thanks!

    • Reeni says

      I think that would work out ok Shala but I’m not 100% sure! I’m more worried about the sauce separating than the noodles. That can sometimes happen with cream sauces like this. Let me know how it works out!

      • Shala says

        Thanks! I’m making it for my friend’s 35th birthday today! I better not experiment this time…but I will definitely give it a whirl next go ’round!

  4. Christie says

    I found this on Pinterest and made it last night! It was delicious! I changed one thing but that’s just my preference. I used wonton wrappers on muffin tins rather than lasagna. It was so delicious that my toddler has said it’s her new favorite food and my husband wants it twice a month!

    • Reeni says

      Thank-you Christie! I’m glad it was a big winner with your family! I love your idea of using muffin tins and wonton wrappers!

  5. Debora Cadene says

    This looks and sounds really good.My husband is a hater of Parmesan cheese… .. I do try and sneak it in to my cooking, but he always knows. (weird..) Anyhow….Does the sauce taste parmasan-y, or can you even tell its in there? I am going to make it just wondering.


    • Reeni says

      Hi Debbie! You can taste the Parmesan! You can use something different or just leave it out entirely. There’s already so much cheese in it you won’t miss it and the sauce is fine without it.

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>