Artichoke Chicken and Spinach Lasagna

Artichoke Chicken and Spinach Lasagna

Classic lasagna gets a modern twist in this delectable artichoke, chicken and spinach lasagna. You’ll find some of the usual suspects like ricotta and mozzarella but a creamy Parmesan sauce takes the place of tomato sauce.

It all adds up to layer upon layer of decadence. Tasty, tender pieces of chicken with the bite of tangy artichokes and fresh baby spinach surrounded by oodles of cheese all held together by a rich sauce and layers of fresh pasta noodles.


I can’t tell you how fast this disappeared. I ate leftovers for breakfast the next day and the vegetable hater in my house ate more than his fair share.

To save time use fresh pasta noodles you can find in the refrigerated pasta section of your market or use the no-bake kind so you can skip that step of boiling the noodles. My Mom swears by the Barila brand – she uses them without fail all the time.

Chicken and Spinach Artichoke  Lasagna

Anyone who’s made a lasagna before knows there’s two things to worry about most. One is that it holds together and second that it isn’t dry. There’s a fine line between too much sauce and just the right amount.

I pulled it off.

This has the perfect amount of sauce so as not to be dry but not so much that the layers slide off each other. Not that there’s anything wrong with that. Some of the most delicious lasagna I’ve ever eaten was one hot mess that just collapsed into a saucy pile when served.

This is not that but something other worldly delicious.

Artichoke Chicken Lasagna

Artichoke Chicken and Spinach Lasagna

Rating: 51

Prep Time: 1 hour

Cook Time: 50 minutes

Yield: 12 squares

Artichoke Chicken and Spinach Lasagna

Classic lasagna gets a modern twist in this delectable artichoke, chicken and spinach lasagna.


2 tablespoons olive oil
1/4 cup diced onion
4 cloves garlic, minced
1 pound boneless chicken breasts, cut into cubes
1 teaspoon Italian seasoning
coarse salt and fresh black pepper
2 (14 ounce) cans (or frozen) artichoke hearts, well-drained
2 cups ricotta Cheese
2 cups fresh shredded mozzarella cheese, divided
1 beaten egg
1 tablespoon fresh chopped parsley
3 cups fresh baby spinach leaves, stems removed
1 pound lasagna noodles, preferably fresh
4 tablespoons butter
1/4 cup all-purpose flour
2 cups whole milk
dash of nutmeg
1/2 cup fresh grated Parmesan cheese
coarse salt and fresh black pepper


  1. In a large skillet heat the olive oil over medium-low heat. Add the onion, garlic, chicken, Italian seasoning and season well with salt and pepper.
  2. Cook, stirring often until chicken is cooked through. Cut the artichokes in half and then in half again, dry off any moisture with paper towels. Stir them into the chicken and cook 2 - 3 minutes. Remove from heat and allow to cool.
  3. In a large mixing bowl combine the ricotta, 1 + 1/2 cups of the mozzarella, the egg and parsley.
  4. Make stacks out of the spinach leaves and cut them into thin strips (chiffonade). Mix them into the ricotta mixture - it will be thick.
  5. Make the sauce:
  6. In a large, heavy duty saucepan melt the butter over medium-low heat. Whisk in flour and cook 3 - 4 minutes, whisking often. Slowly whisk in milk, turn heat up and bring to a simmer.
  7. Maintain a simmer for 4 minutes, stirring often. Turn heat down to low and stir in nutmeg, Parmesan cheese and a pinch or two each of salt and pepper, continue stirring until cheese is melted. Remove from heat.
  8. If using dried noodles cook according to package directions.
  9. Assemble the lasagna:
  10. Preheat oven to 375 degrees F. Butter a 9 x 13-inch casserole pan.
  11. Add a very thin layer of sauce over bottom of the pan, then a layer of noodles covering the bottom completely from edge to edge. Spread 1/2 the ricotta mixture evenly from edge to edge then top with 1/3 of the chicken mixture followed by 1/3 of the sauce.
  12. Cover the filling with another layer of noodles followed with the remaining 1/2 of ricotta, 1/3 of the chicken and 1/3 of the sauce.
  13. Cover with another layer of noodles followed by the remaining sauce, the remaining chicken mixture and the 1/2 cup mozzarella cheese.
  14. Bake 45 - 50 minutes until bubbly and hot in the middle. If the top starts to get too brown tent with aluminum foil. Allow to set 5 - 10 minutes before cutting into squares and serving.


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  1. Catherine Isernia says

    If using non fresh lasagna noodles, do you recommend to fully or partially cook the noodles before assembly.

    • Reeni says

      Hi Sarah! No – not unbaked! The sauce will separate and it won’t turn out the same. It can get watery and taste weird. It’s best when made and eaten fresh.

      • Anna Myatt says

        Funny, cause I made it last night and didn’t make it till tonight, and my husband and I still LOVED it. Didn’t make any difference at all.

  2. Anna Myatt says

    I made this tonight for company. I am allergic to tomatoes, so a lasagna without tomatoes makes me giddy. It went great, but, being a cook myself, there are a few things I will change in the future…

    1.More garlic. I love garlic, and I think a tad more will really accent the artichokes better and give it a more full flavor.

    2. Do not use no boil noodles. I did, and next time I won’t. There was not quite enough sauce to really soften the no boil noodles.

    3. Up the sauce by half. It really needed a tad more to really create an even taste in each bite.

    Otherwise, it is a great recipe! Thanks!

  3. jill says

    Loved this reciepe but I think I will omit the last layer of noodles. Still it was awesome everyone enjoyed it Thanks!!!!

    • Reeni says

      Hi Amanda! Not uncooked! The sauce will separate and it will be unappetizing. It is really best made and eaten fresh.

  4. Meg says

    My husband & I both have allergies to tomato, but we love Italian food, so finding non-tomato versions of dishes is a challenge. This sounds delicious, I think I’ll make it later this week. Thanks for sharing!

  5. Anne Louise Klein says

    I do believe I will make this for our Christmas Eve dinner. Served with garlic bread and salad. I always try to make something a little different for this meal each year. This will work perfect.

  6. Alden says

    This recipe was amazing! I prepared it exactly as written and My husband and I enjoyed every bite! Thank you so much this will be a recipe I will definitely make again.

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